〔Abstract〕 Objective To explore osteogenic properties of strontium doped TiO2nanotube implants. Methods TiO2nanotubes were prepared on the surface of pure titanium by anodic oxidation, strontium was doped into TiO2nanotubes by hydrothermal reaction to construct a new implant coating. The coating's surface morphology,element distribution,crystal phase,hydrophilicity and the release concentration of Sr2+in the coating were detected by scanning emission electron microscopy,X-ray diffraction,atomic force microscopy,surface contact angle measurement instrument and inductively coupled plasma spectrometer. The cytocompatibility and osteogenic activity of MC3T3-E1 on the coating were evaluated by cytological test in vitro,and the osteogenic effect of strontium doped TiO2nanotube implants in vivo was analyzed by Micro-CT. Results Sr was successfully incorporated into TiO2nanotube,mainly in the form of strontium titanate. The surface roughness of the coating had no significant change compared with that of TiO2nanotube,and the hydrophilicity of the coating increased significantly; the strontium doped TiO2nanotube coating promoted the cell adhesion and proliferation,and increased the alkaline phosphatase activity. The strontium doped TiO2nanotube coating implant significantly increased the bone volume fraction around the implant. Conclusion Sr doped TiO2nanotube coating implants show good biocompatibility and osteogenic activity,which can promote bone formation.