〔Abstract〕 Objective To screen the diagnostic indicators of obese patients with obstructive sleep apnea(OSA) and to evaluate the screening effect of these indicators in obese patients with OSA. Methods Retrospective analysis was performed in 32 patients with simple obesity and 87 patients with obesity combined with OSA. The general data were improved and polysomnography( PSG) was performed on the night after admission,and in the morning after PSG monitoring,oral glucose tolerance test( OGTT),serum glycosylated hemoglobin( Hb A1 c),fasting plasma glucose( FPG) and postprandial 2 hours plasma glucose( 2 hPG) were measured to analyze the clinical characteristics and influencing factors of obesity complicated with OSA. Results Multivariate Logistic regression analysis showed that the independent influencing factors of OSA included neck circumference and HbA1 c. The analysis of the working characteristic curve of the subjects( ROC) showed that the area under the curve( AUC) of HbA1 c and neck circumference were 0. 813 and 0. 909 respectively,which were better than the Epworth sleepiness scale and STOP-Bang rating scale( AUC: 0. 638、0. 739). The combined use of Hb A1 c and neck circumference could improve AUC to 0. 934,with a sensitivity of 85. 1% and specificity of 96. 9% in the diagnosis of obese patients with OSA. Conclusion For obese patients,the combined detection of neck circumference and Hb A1 c has good sensitivity and specificity,which can be used for screening obese patients with OSA.