〔Abstract〕 Objective To study the risk factors of neovascular glaucoma(NVG) and the efficacy of panrentinal photocoagulation(PRP) technology combined with conbercept.Methods 112 patients(112 eyes) with NVG were selected as the disease group, and the healthy people of the same age were selected as the healthy group. The general data of the patients was collected and the logistic regression was used to analyze the risk factors of NVG. The patients were divided into the study group(66 cases) and the control group(46 cases) according to the treatment method. The control group underwent traditional ciliary body cryotherapy, and the study group was treated with intravitreal injection of conbercept and PRP. The effects of different treatment methods on efficacy, intraocular pressure,vision and serum factors were compared. Results The results of logistics regression analysis showed that the levels of serum platelet-derived growth factor-C( PDGF-C),vascular endothelial growth factor( VEGF),tumor necrosis factor-α( TNF-α),and interleukin 6( IL-6) were independent risk factors for NVG. The total effective rate of the study group was higher than that of the control group( 95. 45% vs 82. 61%),and the regression time of the study group was shorter than that of the control group( P<0. 05). After treatment,the intraocular pressure in both groups decreased,and the intraocular pressure level of the study group was better than that of the control group at each time point( P<0. 05). After treatment,the best corrected visual acuity( BCVA) of the patients in the two groups increased,and the BCVA of the study group was higher than that of the control group at each time point( P<0. 05). The levels of serum PDGF-C,VEGF,TNF-α and IL-6 in the study group were lower than those in the control group 1 month after treatment( P<0. 05). Conclusion Serum PDGF-C,VEGF,TNF-α and IL-6 are all risk factors for NVG. The combination of PRP technology and conbercept can improve the patient's intraocular pressure and vision,as well as improve the serum inflammatory factors and angiogenesis factors levels,thereby improving the therapeutic effect.