Symptom network analysis of comorbid anxiety and depression in pregnant women

Acta Universitatis Medicinalis Anhui 2025, 06, v.60 1091-1098     font:big middle small

Found programs: National Natural Science Foundation of China(No.82360669);Project of Key Laboratory of Population Health and Eugenics in Anhui Province(No.JKYS20231);“The 14th Five-Year Plan” Characteristic Discipline Project of Colleges and Universities in Xinjiang Uyghur Autonomous Region-Public Health and Preventive Medicine(No.112 Xinjiao Han[2022]);Graduate Student Innovation Project of Xinjiang Medical University,School of Public Health(No.CXCYGW2025005)

Authors:Bahedana Sailike; Meng Weicui ;Wang Xiaoting; Sufeila; Shalayiding; Jiang Ting

Keywords:pregnant women; anxiety; depression; comorbidity; network analysis;

DOI:10.19405/j.cnki.issn1000-1492.2025.06.017

〔Abstract〕 Objective To explore the relationship between the nodes of anxiety and depression symptoms in pregnant women,and to analyze the interaction between these symptoms.Methods A convenient sampling method was used to evaluate the level of anxiety and depression among pregnant women who underwent antenatal check-up in the obstetric examination in a Grade Ⅲ A hospital.Data were collected using the General Data Questionnaire,the Generalized Anxiety Disorder Scale(GAD-7),and the Patient Health Questionnaire Depression Scale(PHQ-9).Based on the relationship between anxiety and depressive symptoms in pregnant women,a network was constructed and analyzed.Results Among the 1 742 subjects,476(27.3%) had anxiety,290(16.6%) had depression,and 218(12.5%) had anxiety and depression comorbidities.The univariate analysis revealed statistically significant differences in various factors such as age,education level,occupation,gestational week,sleep status during pregnancy,exercise status during pregnancy,drinking,knowledge of pregnancy,planned pregnancy,living environment,husband-wife relationship,parent-in-law relationship and parental relationship had statistically significant differences in whether they had CAD(all P