〔Abstract〕 Objective To investigate the correlation between the pan-immune inflammation value(PIV) and clinical and pathological features of primary IgA nephropathy(IgAN), and to evaluate the clinical significance of PIV in primary IgAN. Methods 200 patients with primary IgAN diagnosed by renal biopsy were selected as the research subjects. General information, laboratory indicators, pathologic features of renal biopsy, and calculations of platelet to lymphocyte count ratio(PLR), neutrophil to lymphocyte count ratio(NLR), PIV, and other relevant indices about patients were collected. According to the median PIV, subjects were divided into low PIV group(PIV≤194.81) and high PIV group(PIV >194.81), and the clinical and pathological data of the two groups were compared and analyzed. Using Spearman rank correlation analysis and logistic regression analysis, the relationship between PIV and primary IgAN in terms of clinical and pathological aspects was explored. Results There were statistical significance in age, gender, height, hyperuricemia, hemoglobin, absolute neutrophil count(ANC), absolute monocytes count, platelet, PLR, NLR, serum uric acid, immunoglobulin G(IgG), immunoglobulin A(IgA)/complement 3(C3), and fusion degree of the podocyte foot between the two sets(P