〔Abstract〕 To investigate the impact of endometriosis on pregnancy and delivery outcomes in patients undergoing single euploid frozen⁃thawed blastocyst transfer cycles following preimplantation genetic testing. Meth-transfer after preimplantation genetic testing at the reproductive center of The First Affiliated Hospital of Anhui Med⁃ ical University. The endometriosis group comprised 84 treatment cycles. After 1 ∶ 3 propensity score matching , 252 treatment cycles from non⁃endometriosis patients were included as the control group. General characteristics and ences between the two groups in terms of general characteristics , human chorionic gonadotropin ( HCG) positive rate , cycle clinical pregnancy rate per cycle , early miscarriage rate , preterm birth rate , live birth rate per cycle ,cesarean section rate , delivery weeks , cumulative clinical pregnancy rate , and cumulative live birth rate (all P >0. 05) . Conclusion Endometriosis may not reduce the pregnancy rate and live birth rate in single frozen euploid blastocyst transfer cycles.