Found programs: National Natural Science Foundation of China ( No . 81560783 , 82060880 , 81860865 ) ; Key Research and Development Program of Jiangxi Province (No . 20223BBG71012) ; the First Batch of Scientific and Technological Innovation Team Project of Jiangxi University of Chinese Medicine (No . CXTD22013) ; Science and Technology Research Project of Jiangxi Provincial Department of Education ( No . GJJ2200915) ; Natural Science Foundation of Jiangxi Province ( No . 20202BAB206073 ) ; Special Fund for Science and Technology of Jiangxi Province (No . 20232BAB216115)
Authors：Liu Shuzhen1 , Peng Jiahua1 , 2 , Xiao Min1 , Liang Ruining1 , 2 , 3
Keywords：CCAAT/enhancer binding protein β; reproduction; follicular development; decidualization; polycys- tic ovary syndrome
DOI：10.19405/j.cnki.issn1000-1492.2025.11.025
〔Abstract〕 CCAAT/enhancer binding protein β(C/EBPβ) is a transcription factor that plays a vital role in diverse biological processes , including cell proliferation , cell apoptosis , inflammation , and immune regulation . It is ex- pressed in female reproductive organs such as the ovary and uterus , and it serves as a critical regulator of both physiological functions and pathological conditions . This review comprehensively summarizes the significant contri- butions of C/EBPβto physiological processes such as follicular development and decidualization , as well as its in- volvements and mechanisms in reproductive disorders including polycystic ovary syndrome , endometriosis , and o- varian tumors , aiming to provide a potential research target in the field of reproduction .