〔Abstract〕 Objective To understand the epidemiological and spatial distribution characteristics of mushroom poisoning events in Zunyi, and to provide theoretical basis for the prevention of mushroom poisoning at the grassroots level. Methods Descriptive analysis and spatial distribution of mushroom poisoning events reported by foodborne disease surveillance system in Zunyi were carried out. Results A total of 525 cases of mushroom poisoning events were reported in Zunyi in the past ten years, with a total of 1 758 cases poisoning casesand 29 deaths. The occurrence of mushroom poisoning had seasonal fluctuation, mainly from June to October, accounting for 89.90% of the total. Family was the main place of mushroom poisoning, accounting for 96% of the total. Autochthonous gathering was the main source of mushroom poisoning events. Conclusion Mushroom poisoning is one of the main causes of food poisoning death. With the help of geographic information system(GIS), the distribution map of toadstools is preliminarily explored by combining environmental factors with the distribution of mushroom types.