Found programs: National Natural Science Foundation of China ( No . 22176132) ; Shenzhen Medical Research Fund (No . B2403008) ; Project of Shenzhen Science and Technology Innovation Commission (No . JCYJ20210324135000001) ; Guangdong Medical Science Research Fund (No . A2023276)
Authors：Zhao Xinyue1 , 2 , Shi Xiaolei 1 , 2 , Hu Lianghao3 , Lu Guotao1 , 2 , Pan Jiajia4
Keywords：acute pancreatitis; relapse; lipid levels; follow-up; rick factors; linear mixed model;
DOI：10.19405/j.cnki.issn1000-1492.2025.12.018
〔Abstract〕 Objective To analyze the temporal changes in lipid levels in patients following acute pancreatitis(AP) and explore the factors associated with post-AP serum triglyceride(TG) level changes. Methods Patients diagnosed with AP were included in this study. Clinical data were collected retrospectively, and lipid profile data from follow-up visits after discharge were tracked. Kaplan-Meier(K-M) curves were used to stratify follow-up duration, while Spearman correlation analysis assessed the relationship between lipid levels and follow-up time. A linear regression model was used to investigate factors influencing TG level changes post-AP. Results A total of 141 patients with 306 follow-up visits were included. Spearman correlation analysis showed a mild increase in lipid levels over time post-discharge: TG(r=0.159, P=0.005), total cholesterol(TC)(r=0.231, P