〔Abstract〕 To investigate somatization symptoms in adolescents during frequent earthquakes in Hefei， and to explore their correlation with earthquake experiences. Methods A cross-sectional survey was used to select 324 adolescents in Hefei as the survey objects. The self-rating scale of somatization symptoms（SSS）and the fa- tigue intensity scale（FIS）were used to evaluate the somatization symptoms and fatigue degree of middle school stu- dents，and multivariate Logistic regression analysis was used to explore the related factors of somatization symp - toms and fatigue among middle school students. Results A total of 324 adolescents were included，and the overall detection rate of somatization symptoms was 6. 5% ，and the detection rate of moderate or above fatigue was 20. 1%. The results of regression analysis showed that adolescents who were concerned about the earthquake for a longer time (≥1 h）had a higher risk of somatization symptoms（OR=5. 430，95%CI：1. 547-19. 058），and adoles- cents who received pre-earthquake training had a lower degree of fatigue（OR=0. 535，95%CI：0. 292-0. 981）（P< 0. 05）. Conclusion During the frequent earthquakes，adolescents have more somatization symptoms and fatigue. Therefore，it is crucial to enhance health education，reduce the emphasis on event-related reports，and implement earthquake prevention and disaster reduction training to improve the physical and mental health of adolescents.