〔Abstract〕 To analyze the long-term trend of incidence and mortality of type 2 diabetic kidney disease （DKD）in China from 1990 to 2021. Methods The Joinpoint regression model was used to analyze the average an- nual percentage change（ AAPC ）of standardized incidence rate and standardized mortality rate ，and the age- period-cohort（APC）model was constructed to analyze the longitudinal age change，period and cohort effect risk ra- tio（RR）. Results From 1990 to 2021，the standardized incidence rate of type 2 DKD in males and females showed an overall upward trend，with AAPC of 0. 08% and 0. 36%，respectively. The age-standardized mortality rate of the total population and female showed a downward trend，with AAPC of -0. 61% and -1. 03%，respec- tively. However，there was no significant difference in males. APC model showed that the age effect existed：the peak age was 75-79 years old，the mortality rate of females increased，and the mortality rate of males decreased af- ter 80-84 years old. For the effect of time period，the risk of type 2 DKD incidence in females in 2017-2021 was 1. 05 times that in 2002-2006，and the risk of death in males and females in 2017-2021 was 0. 84 and 0. 71 times that in 2002-2006，respectively. For cohort effects，the highest risk of disease was seen in men and women born in 1967-1971，and the highest risk of death was seen in men born in 1952-1956 and women born in 1912-1916. Con ⁃ clusion From 1990 to 2021，the standardized incidence rate of type 2 DKD in China shows an upward trend，and the standardized mortality rate shows a downward trend. It is necessary to strengthen the health behavior publicity and education of type 2 DKD，and actively carry out early screening to reduce the disease burden.