Risk factors and etiological characteristics of urinary tract infection in continuous ambulatory peritoneal dialysis patients

Acta Universitatis Medicinalis Anhui 2021 10 v.56 1656-1660     font:big middle small

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Authors:Luo Xiaomei; Zhang Pei; Qi Xiangming; Wu Yonggui

Keywords:peritoneal dialysis;urinary tract infection;bacterial infection;urine culture

DOI:10.19405/j.cnki.issn1000-1492.2021.10.029

〔Abstract〕 Objective To investigate the risk factors and etiological characteristics of urinary tract infection in continuous ambulatory peritoneal dialysis(CAPD) patients. Methods A total of 90 CAPD patients with urinary tract infection in the past 5 years were selected as the infection group. In addition, 36 patients with CAPD without urinary tract infection were selected as the control group. The clinical characteristics of the two groups were compared. The risk factors of urinary tract infection and the etiological characteristics were analyzed. Results A total of 90 strains of bacteria were isolated from the urine culture of 90 CAPD patients with urinary tract infection.Escherichia coli,Enterococcus faecalisandKlebsiella pneumoniaewere the most common bacteria. The proportion of women in the urinary tract infection group was 84.4%, which was higher than 38.9% in the control group(χ2=26.149,P<0.001). The proportion of people with 24-hour urine volume less than 200 ml was about 50% in the infection group, which was higher than 16.7% in the control group(χ2=11.859,P<0.05). The peritoneal dialysis age, total cholesterol, triglycerides, fasting blood glucose, blood calcium, calcium and phosphorus product of the urinary tract infection group were higher than those of the control group(P<0.05). Multivariate binary logistic regression analysis indicated that female was an independent risk factor for urinary tract infections(OR=6.218,P=0.001). Conclusion Urinary tract infections in peritoneal dialysis patients are more common with Gram-negative bacteria. The urinary tract infection group has the characteristics of long dialysis age, higher total cholesterol, triglycerides, fasting blood glucose, blood calcium, calcium and phosphorus product, and low urine volume over 24 hours compared to the control group. Female is an independent risk factor for urinary tract infections.