〔Abstract〕 Objective To investigate the effect of atosiban on frozen-thawed embryo transfer outcomes in infertile patients with scar uterus. Methods This was a retrospective study.278 secondary infertile patients with cesarean scar uterus were divided into two groups, the study group(n=128) treated with low-dose atosiban(6.75 mg/0.9 ml, iv) within 30 min before fozen-thawed embryo transfer, while the control group(n=150) without treatment with atosiban.Then the two groups were respectively stratified according to the times of embryo transfer, which were the first time, second time and third time or more.The differences of embryo implantation rate, biochemical pregnancy rate, clinical pregnancy rate and live birth rate between study group and control group were compared. Results The embryo implantation rate, biochemical pregnancy rate, clinical pregnancy rate and live birth rate of the overall study group were improved, but the difference was not statistically significant(P>0.05); atosiban could greatly improve the transfer outcomes of patients in the second embryo transfer, but the difference was not statistically significant(P>0.05). Conclusion Treatment with atosiban before frozen-thawed embryo transfer can′t significantly improve transfer outcomes of infertile patients with scar uterus.