〔Abstract〕 Objective To probe into the influencing factors of subendocardial viability ratio(SEVR) based on pulse wave analysis. Methods Height, weight and blood pressure were measured in 592 physical examination subjects. Fasting venous blood was collected to analyze blood glucose, blood lipids and other biochemical indicators. Pulse wave pressure waveforms were collected with cardiac function instruments of the Chinese academy of sciences, and SEVR values were calculated based on diastolic and systolic area. Results Multivariate linear regression analysis showed that SEVR values were significantly different between males and females(P<0.05), heart rate was negatively correlated with SEVR values(P<0.05), and creatinine was positively correlated with SEVR values(P<0.05). Conclusion Gender, heart rate and serum creatinine may be the main influencing factors of SEVR value. According to this study, SEVR is a non-invasive evaluation indicator of myocardial perfusion with few interferences, which has certain clinical application value.