〔Abstract〕 Objective This study aims to explore the general rules of profile-based forehead protrusion value and appearance in Anhui province, and the results will provide guidance for clinical orthodontic works on matching lateral forehead protrusion and the lower third of the face in the future. Methods A total of 262 patients were included in this cross-sectional study. The materials for the study were the lateral cephalometric radiographs and standard 90-degree profile photographs taken from the subjects at the same time. The Frankfurt horizontal(FH) plane was used to calibrate the head position parallel to the ground. The samples were grouped according to genders, ages and dentoskeletal classifications. The measurement points of forehead protrusion in profile included hairline point and soft tissue nasion point. The point where the parallel line connecting two points was tangent to the forehead contour was defined as the most convex point. The value of forehead protrusion in profile was expressed by the distance between two parallel lines. The forehead morphology was studied by tracing the forehead on lateral photographs.Pvalues<0.05 were considered statistically significant. Results The lateral forehead protrusion of female was larger than that of male, and the difference between male and female decreased gradually from children(P<0.001), adolescents(P<0.001) to adults. The shape of the forehead differed between the two sexes. Female forehead is round, protruding part in the middle, the overall appearance like an arc; Male forehead was more straight, the most convex point was generally located near the eyebrow arch. Conclusion Gender is an important factor influencing profile forehead protrusion and appearance. The difference between male and female forehead protrusion decreases with age. But the shape remains different.