〔Abstract〕 Objective To compare pregnancy outcomes among pregnant women undergoing cervical polypectomy during different gestational periods. Methods A total of 125 pregnant women were diagnosed with cervical polyps and underwent surgical removal. These participants were divided into the natural pregnancy group(n=71) and thein vitrofertilization and embryo transfer group(IVF-ET group,n=54). Retrospective analysis was conducted on various clinical parameters including age, gestational times, delivery times, abortion times, history of adverse pregnancy outcomes, history of endometrial polyps, pre-polyp removal vaginal bleeding episodes, gestational age at the time of polyp removal procedure, number of polyps detected during surgery, postoperative pathology results as well as pregnancy outcomes. Results Vaginal bleeding was the most common symptom of pregnancy combined with cervical polyps, accounting for 111 cases(88.8%)(62 cases in the natural pregnancy group(87.32%) and 49 cases in the IVF-ET group(90.74%)). Some patients had increased vaginal discharge or were found during a gynecological exam, accounting for 11.2% of the patients. All patients underwent cervical polypectomy during pregnancy, except for 9 cases of continued pregnancy(4 cases in the natural pregnancy group and 5 cases in the IVF-ET group), of which 13 had miscarriage, 10 had preterm birth(6 in the natural pregnancy group and 4 in the IVF group)and 93(54 cases in natural pregnancy group, 39 cases in IVF group)(74.4%) delivered at full term. Postoperative pathology was mostly inflammatory polyps(105 cases, 84%), deciduous polyps(20 cases, 8%)(10 cases in the natural pregnancy group and 10 cases in the IVF-ET group, 14.09% and 18.52%, respectively). The incidence of preoperative vaginal bleeding, decidual polyp, postoperative abortion, and postoperative preterm birth in the IVF-ET group exhibited higher rates compared to those observed in the natural pregnancy group; however, these differences did not reach statistical significance. Conclusion The cervical polypectomy procedure was performed during pregnancy for both the natural conception group and the IVF-ET group, with no significant disparity observed in pregnancy outcomes between these two cohorts.